Staffed 24 hours a day, 7 days a week, the coverage area for the Culberson Hospital EMS encompasses all 3,812 square miles of Culberson County, including the Town of Van Horn as well as the more remote areas of the county such as the Guadalupe Mountains National Park and various wind turbine sites located in the surrounding mountains. In addition, the Culberson Hospital EMS covers about 120 miles of Interstate 10. The Average Daily Traffic count for Interstate 10 indicates that over 15,500 motor vehicles travel through Van Horn daily, resulting in an estimated annual average traffic count of 5.7 million motor vehicles. This number does not include north and south traffic on U.S. Highway 90 and State Highway 54.  

Based on patient origin data, care provided is provided to numerous individuals from other parts of Texas, as well as the United States, living in 300 different zip codes.